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Dietary supplement
L-Ornithine-L-Aspartate
Support for the ornithine cycle
Tested microbiologically, for heavy metals and ethylene oxide
Servings per container: 70
159,99 zł 148,14 zł
270 in stock
Free delivery within Poland from 250 zł
Previous lowest price was 159,99 zł.
A combination of L-Ornithine and Aspartic Acid in powder form.
Dietary supplement
L-Ornithine-L-Aspartate
Support for the ornithine cycle
Tested microbiologically, for heavy metals and ethylene oxide
Servings per container: 70
159,99 zł 148,14 zł
270 in stock
Previous lowest price was 159,99 zł.
Free delivery within Poland from 250 zł
Gwarancja bezpiecznych zakupów. Otrzymasz swój produkt albo zwrot pieniędzy. Zobacz szczegóły
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L-Ornithine-L-Aspartate is a powdered dietary supplement containing L-ornithine L-aspartate. The product is recommended for adults to supplement their daily diet with L-ornithine L-aspartate.
L-ornithine aspartate is a stable salt of the two very important amino acids: L-ornithine and aspartic acid.
| Ingredient | Amount per daily serving 2 measuring cups |
| L-Ornithine L-Aspartate | 1000 mg |
Ingredients: L-Ornithine L-Aspartate.
Gluten-free.
Net weight: 70 g
Take 1000 mg daily (corresponding to 2 flat measuring cups provided with the container).
Recommended intake: dissolve in a teaspoon of water or in a small amount of water (the supplement is tasteless) and take before the evening meal. You can divide servings into smaller portions and take several times a day, always before food.
Do not exceed suggested use. A varied diet and a healthy lifestyle are necessary to maintain good health. Dietary supplements should not replace a varied diet. The product is recommended for adults. The product is suitable for vegans.
Warning: if pregnant or nursing, consult your doctor before use.
Organoleptic properties: white tasteless powder of specific odour, easily soluble in water. After opening the container, the product may naturally become clumpy if exposed to humidity.
Batch tests performed towards:
- Microbiology: the presence of listeria, staphylococcus, Escherichia coli and coli groups, salmonella, total microbial count,
- Presence of: echimidine and heliosupine, erucifolin, europine, heliotrin, intermedina, jacobin, lasjocarpine, licopsamine and indicine, monocrotaline, echimidine N-oxide, erucifolin N-oxide, europine N-oxide, heliosupine N-oxide, heliothrin N-oxide, N -intermedin oxide, indicin N-oxide, echinatin N-oxide, rinderine N-oxide, jacobin N-oxide, lasiocarpine N-oxide, lycopsamine N-oxide, monocrotaline N-oxide, retrorzyne N-oxide, usaramine N-oxide, N-oxide senecionine, integerrimine N-oxide, senecyvernine N-oxide, seneciphylline N-oxide, sparthioidine N-oxide, retrorzyne, usaramine, rinderine and echinatin, seneciphylline, sparthioidine, senecivernine, integerrymine, senecionine, senkirkine, trichodesmin, atropine, scopolamine, the presence of pyrrolizidine and tropane alkaloids,
- heavy metals (arsenic, cadmium, lead, mercury),
- ethylene oxide and 2-chloroethanol,
- gluten content.
The tests were carried out at the independent, accredited Laboratorium GBA Polska – Certificates of Accreditation no: AB 1095.
Keep away from the sun at a temperature below 25°C, in the original packaging and out of reach of small children. The product naturally turns clumpy. Store the product in a dry place. Exposure to moisture will make the product clump faster. Clumping does not affect the properties of the substance.
Storage: after the first opening, store in a dry place in the tightly closed original packaging. We recommend storing the product in the refrigerator. Protect from light and moisture.
Production lot number / Best before – see the unit label (left side of the label).
LOLA, a combination of L-Ornithine and Aspartic Acid
The ornithine cycle is a cycle of the decomposition of ammonia. The ornithine cycle is also known as the urea cycle or the Krebs urea cycle.
The urea cycle is the primary metabolic pathway in which ammonia is broken down and urea synthesised. Ammonia is converted into particular amino acids to eventually become urea, which will be excreted from the body with urine, and in small amounts with sweat. Two amino acids: ornithine and aspartate, as well as the cellular energy, i.e. ATP, are necessary for particular conversions of ammonia.
Sikorska H, Cianciara J, Wiercińska-Drapało A. Fizjologiczne funkcje L-ornityny i L-asparaginianu oraz celowość podawania asparaginianu ornityny w stanach wzglednego niedoboru. Pol Merkur Lekarski. 2010 Jun;28(168):490-5. Polish. PMID: 20642112.
The urea cycle is a sequence of consecutive enzymatic reactions of three amino acids: ornithine, citrulline and arginine.
The metabolic cycle of the above amino acids results in the production of urea from ammonia, carbon dioxide and aspartate.
The decomposition of the amino acid ornithine, following the transfer of the amino group (-NH2), results in the formation, through transamination reaction, of four molecules: α-Ketoglutarate, glutamate, oxaloacetate and pyruvate.
These amino acids are secreted into the blood and then get transported to the liver, where alanine is transaminated together with aspartate and their amino groups are transferred to α-ketoglutarate to form glutamate or to glutamate to form glutamine. Glutamate then undergoes a chemical reaction in which it loses its amino group and the resulting ammonium ion is immediately converted to carbamoyl phosphate. The latter is involved in the ornithine cycle.
The ammonium ion is a highly toxic substance and must therefore be decomposed to a water-soluble and less toxic substance, urea. It gives the human body a chance to get rid of all the by-products and waste products of metabolism.
Ahmad I, Khan AA, Alam A, Dilshad A, Butt AK, Shafqat F, Malik K, Sarwar S. L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy. J Coll Physicians Surg Pak. 2008 Nov;18(11):684-7. PMID: 18983791.
The entire ornithine cycle takes place in the mitochondria and hepatocytes, i.e. liver cells. It is directly linked to the proper Krebs cycle via the electron transport chain, adenosine triphosphate (ATP) as the cell’s energy carrier, and fumaric and aspartic acids. The main product of metabolism is urea.
References:
Stauch S, Kircheis G, Adler G, Beckh K, Ditschuneit H, Görtelmeyer R, Hendricks R, Heuser A, Karoff C, Malfertheiner P, Mayer D, Rösch W, Steffens J. Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study. J Hepatol. 1998 May;28(5):856-64. doi: 10.1016/s0168-8278(98)80237-7. PMID: 9625322.
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